Glycerol-3-phosphate acyltransferase 2 expression modulates cell roughness and membrane permeability: An atomic force microscopy study.
In mammalian cells, de novo glycerolipid synthesis begins with the acylation of glycerol-3-phosphate, catalyzed by glycerol-3-phosphate acyltransferases (GPAT).GPAT2 is a mitochondrial isoform primarily expressed click here in testis under physiological conditions, and overexpressed in several types of cancers and cancer-derived human cell lines wh